What is the Endocannabinoid System?

Its hard to believe but just like the cannabis plant, humans actually have naturally occurring cannabinoids as well, which are called “endocannabinoids” (the cannabinoids that occur in cannabis plants are called phyto-cannabinoids”).

The two primary endocannabinoids in the human body are anandamide and 2-AG (2-arachidonoylglycerol). Easily explained you could consider these two molecules to be the “human” versions of THC and CBD.

Also, it’s important to understand that these compounds are produced entirely naturally by the human body – each and every one of us has them, regardless of whether we’ve ever smoked weed before or not.

In terms of function, endocannabinoids work by interacting with their corresponding receptors, which are named endocannabinoid receptors. It appears that by far the most important of these internal receptors are CB-1 and CB-2, with CB-1 primarily influencing activity on the brain and CB-2 primarily influencing immune system activity and interactions with body tissues and organ systems.


The endocannabinoid system (which includes the complete network of cannabinoids and receptors in the body) is so common throughout the human body, that it has been described as a “bridge between body and mind” that is potentially the most important physiologic system involved in establishing and maintaining human health.

Endocannabinoids have been found in abundance throughout the brain, organs, connective tissues, glands, and immune cells, and their activity has been documented to regulate such things as cell-to-cell communication, neurogenesis (new cell production), and even the promotion of apoptosis, which is the death of malignant cancer cells and other non-productive cells through “programmed cellular suicide.”


How Does the Endocannabinoid System Work?

What’s intriguing here,  is the fact that endocannabinoids can accomplish a wide range of “bodily tasks” while still maintaining the singular objective of homeostasis (balance). In other words, even though the endocannabinoid system performs dozens and dozens of different tasks inside the body, it ultimately has one singular goal: to make sure that every bodily system is functioning healthily, efficiently, and in tune with other systems.

One of the best examples of an ECS function in the body is how it works to heal tissue after an injury. When a specific site becomes damaged or injured , anandamide and 2-AG (remember these are the body’s main endocannabinoids) are known to decrease the release of sensitizers from the site of injury, which then prevents excessive nerve cell firing (i.e. minimizes pain) and also prevents immune cells from releasing inflammation-inducing substances.

Likewise, the ECS has similarly profound impacts on the brain, nervous system, and our general psychological and emotional well-being. For instance it’s known that endocannabinoid pathways can directly influence an individual’s response to external stimuli, which has huge implications in terms of being able to alter human behavior responses. More clearly put, the ECS and its network of chemical pathways is believed to be able to directly manipulate (and reverse) the neurological actions that lead to mental disorders like anxiety, depression, and even psychosis. The Real CBD’s CBG oil has been found to help greatly on patients with anxiety and depression. 

Also, by influencing the production of new cells in the central nervous system, it has been suggested that cannabinoids may be able to directly mediate an individual’s “open-mindedness,” as well as their capacity to re-format patterns of thought and behaviour, which is a crucial aspect of being able to adapt to new situations while maintaining a healthy state of mind.

How does cannabis work with the Endocannabinoid System?

So you might be wondering, “if every human being has their own endocannabinoid system, then why do we even need cannabinoids?”

Well, consider this: what do you suppose happens when there’s a deficiency of endocannabinoids, and/or the ECS is not functioning properly in the body? If you guessed that any number of things can go wrong (either physically or psychologically), then you’re exactly right. And this is precisely why cannabis and CBD oils in general – is believed to be able to provide relief from a seemingly endless range of medical conditions. If endocannabinoids like 2-AG and anandamide are responsible for maintaining health and homeostasis on every single cellular level, for instance, then it makes perfect sense that cannabis (with its nearly identically-functioning THC and CBD molecules) can act as a “miracle medicine” in the event of an ECS deficiency.

Also, on a bit of a side note, this is why the popularity of CBD has taken off like a rocket in recent years. It’s, of course, no secret that in addition to its health benefits, cannabis can also provide a mind-altering high, which is undesirable for a large number of people.

CBD on the other hand (which remember is the second-most abundant cannabinoid in cannabis), does not produce any intoxicating effects. It essentially provides all of the health and therapeutic benefits of cannabis, just without the high.


What is the Endocannabinoid System: Final Thoughts

Well, hopefully, your questions (or at least some of them) on what the endocannabinoid system is finally been answered. In short, it is essentially the body’s own “naturally-occurring balancing system” – able to influence any range of mind/body functions in order to promote health and homeostasis on a complete, whole-body level.

So no matter what it is that you might be suffering from – whether it be a psychological condition such as insomnia or anxiety or a physical condition like pain, inflammation, or high blood pressure, CBD oil is likely able to provide safe, effective, and 100% natural relief.

We welcome you to our shop to find exactly what you need.

0 replies

Leave a Reply

Want to join the discussion?
Feel free to contribute!

Leave a Reply