By now, most people familiar with cannabis and hemp have heard of THC (tetrahydrocannabinol) and CBD (cannabidiol) and their effects, but did you know there are many similar compounds in cannabis? And the next one in line for great attention is CBG……
CBG is a non-intoxicating cannabinoid, meaning it doesn’t produce the “high”. Because it is present in low levels (usually less than 1%) in most cannabis strains, CBG is considered a minor cannabinoid. Amazingly, however, both THC and CBD start out as CBG— CBG is the chemical parent of THC and CBD.
CBG is important because of its numerous health benefits, especially for people with disorders affecting the central nervous system, including neurological diseases, depression and anxieties, and chronic pain. It can also affect the body by increasing anandamide levels. Anandamide is a naturally-occurring cannabinoid that helps regulate many biological functions, including appetite, sleep, and memory.
The Real CBD’s new product is 8%CBG and 6%CBD. We have had great reviews of this new oil relieving anxiety and depression. Even some of our furry friends have benefited greatly – a very anxious and timid rescue dog is now playing happily in the park with the other dogs.
What do we know so far about CBG
CBG has shown to block serotonin receptors as well, which suggests a role for CBG in treating depression and anxiety.
It stimulates bone formation and healing. In a 2007 study, the effects of CBG and other cannabinoids on bone marrow cultures were investigated. The results showed that they could stimulate bone marrow stem cells indirectly through the CB2 receptor. This suggests that CBG and other cannabinoids may help with the healing of bone fractures by promoting new bone growth and formation.
In a 2009 review article, CBD, CBG, and CBC along with other cannabinoids were reported to slow the progression and growth of various tumors and cancer cells. By slowing tumor growth, these cannabinoids could extend the life of people who are battling cancer.
Shown to reduce inflammation. Cannabinoids like CBG have the ability to reduce inflammation by targeting specific molecules responsible for inflammation in various disease states, including pain syndromes, cancer, and even inflammatory bowel disease. For example, studies show that CBG can act as a COX-2 inhibitor, similar to widely used pharmaceuticals called non-steroidal anti-inflammatory drugs (NSAIDs).
For psoriasis and skin treatment, CBG and other cannabinoids could be helpful for treating various skin disorders, due to the presence of cannabinoid receptors in the skin.
In 2015 Researchers in Spain focused on the use of CBG to treat Huntington’s disease. This research was mainly through animal trials, but the researchers concluded that CBG could be of use in treating neurological disorders and acted as potent neuroprotection.
A study has just recently been concluded. It examined the effect CBG had on anxiety and depression. As this compound is non-psychoactive, when it is given to those patients who were depressed or anxious, they would not feel the paranoia that can come from treatment with large amounts of THC. Researchers concluded that the use of CBG for treating anxiety and depression worked as well as THC and had no psychoactive effects. CBG directly affected CB2 receptors in the endocannabinoid system in the body, instead of only the CB1 receptors that THC targeted.
In 2015 Researchers in Spain focused on the use of CBG to treat Huntington’s disease. This research was mainly through animal trials, but the researchers concluded that CBG could be of use in treating neurological disorders and acted as potent neuroprotection. CBG was found to be “extremely active as a neuroprotectant.” Treatment with CBG improved movement and recovery in mice with Huntington’s and protected neurons from degeneration. CBG also showed possible anti-inflammatory and antioxidant effects.
The benefits that CBG has to offer
The benefits are closely tied to what it does in the human body. In the right dose, CBG acts as an:
- Analgesic (relieves pain).
- Antibacterial (slows bacteria growth).
- Anti-convulsive (reduces seizures and convulsions).
- Anti-inflammatory (reduces inflammation).
- Anti-insomnia (aids sleep).
- Anti-proliferative (inhibits cancer cell growth).
- Antidepressant (raises mood).
- Bone stimulant (promotes bone growth).
- Brain cell stimulant (promotes neuron growth)
What Disorders can CBG help?
- Inflammatory bowel disease.
- Anti-inflammatory disorders.
- Chronic pain.
- Huntington’s disease.
- Low appetite (resulting from chemotherapy and other treatments).